Generic Viagra

For high blood pressure: Adults—5 mg once a day at first. Then, your doctor may increase your dose to 10 to 40 mg a day taken as a single dose or divided into two doses. Children—Use and dose must be determined by your doctor. For treating weakened heart muscle: Adults—2.5 mg two times a day at first. Then, your doctor may increase your dose up to 20 mg a day taken in divided doses. For injection dosage form: For high blood pressure: Adults—1.25 mg every six hours injected into a vein. Children—Use and dose must be determined by your doctor. For fosinopril For oral dosage form (tablets): For congestive heart failure: Adults—10 mg once a day at first. Then your doctor may increase your dose to 20 to 40 mg once a day. For high blood pressure: Adults—10 to 40 mg once a day. Children—Use and dose must be determined by your doctor. For lisinopril For oral dosage form (tablets): For congestive heart failure: Adults—5 to 20 mg once a day. Children—Use and dose must be determined by your doctor. For high blood pressure: Adults—10 to 40 mg once a day. Children—Use and dose must be determined by your doctor. For immediate treatment after a heart attack: Adults—5 mg once a day at first. Your doctor may increase the dose to 10 mg once a day. Children—Use and dose must be determined by your doctor. For moexipril For oral dosage form (tablets): For high blood pressure: Adults—7.5 mg once a day. Then, your doctor may increase your dose up to 30 mg a day taken as a single dose or divided into two doses. Children—Use and dose must be determined by your doctor. For perindopril For oral dosage form (tablets): For high blood pressure: Adults—4 mg once a day. Then, your doctor may increase your dosage up to 16 mg a day taken as a single dose or divided into two doses. Children—Use and dose must be determined by your doctor. For quinapril For oral dosage form (tablets): For high blood pressure: Adults—10 to 20 mg once a day at first. Then, your doctor may increase your dosage up to 80 mg a day taken as a single dose or divided into two doses. Children—Use and dose must be determined by your doctor. For congestive heart failure: Adults—5 mg twice a day at first. Then, your doctor may increase your dose to 20 to 40 mg a day taken in two divided doses. For ramipril For oral dosage form (capsules): For high blood pressure: Adults—2.5 mg once a day at first. Then, your doctor may increase your dosage up to 20 mg a day taken as a single dose or divided into two doses. Children—Use and dose must be determined by your doctor. For congestive heart failure after a heart attack: Adults—2.5 to 5 mg twice a day. For reducing risk of heart attack, stroke or death from cardiovascular causes Adults— 2.5 mg once a day for one week. For the next three weeks the dose is 5 mg a day, and then increased as needed to 10 mg a day. The dose may be divided if needed.Note: For use in people aged 55 and older. For trandolapril For oral dosage form (tablets): For high blood pressure: Adults—1 to 2 mg once a day at first. Then, your doctor may increase your dose to 2 to 4 mg a day taken as a single or divided into two doses. Children—Use and dose must be determined by your doctor. For treatment after a heart attack: Adults—1 mg once a day at first. Then, your doctor may increase your dose up to 4 mg a day taken as a single or divided into two doses.

Drug Interactions

Other Generic Viagras—Although certain Generic Viagras should not be used together at all, in other cases two different Generic Viagras may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking tamsulosin, it is especially important that your health care professional know if you are taking any of the following: Doxazosin (e.g., Cardura) or Phentolamine or Prazosin (e.g., Minipress) or Terazosin (e.g., Hytrin)—Effects of these medicines or tamsulosin may be increased Warfarin (e.g., Coumadin)—These Generic Viagras should be used together with caution

Common Brand Names

In the U.S.— Flomax

Contraindications

In deciding to use a medicine, the risks of taking the Generic Viagra must be weighed against the good it will do. This is a decision you and your doctor will make. For tamsulosin, the following should be considered: Allergies—Tell your doctor if you have ever had any unusual or allergic reaction to tamsulosin. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes.

Drug

Flomax

Side Effects

Side Effects of Generic Viagra Along with its needed effects, a Generic Viagra may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. The following side effects may go away during treatment as your body adjusts to Generic Viagra. However, check with your doctor if any of the following side effects continue or are bothersome: More common Abnormal ejaculation; back pain; diarrhea; dizziness; headache; stuffy or runny nose; unusual weakness Less common Chest pain; decreased sexual drive or performance; difficulty in sleeping; fainting or lightheadedness, especially when getting up from a lying or sitting position; drowsiness; nausea Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.

Precautions

It is important that your doctor check your progress at regular visits to make sure that this Generic Viagra is working properly. Dizziness, lightheadedness, or fainting may occur after you take this medicine, especially when you get up from a lying or sitting position. Getting up slowly may help lessen this problem. If you feel dizzy, lie down so that you do not faint. Then sit for a few moments before standing to prevent the dizziness from returning. Because tamsulosin may cause some people to become dizzy, make sure you know how you react to this Generic Viagra before you drive, use machines, or do anything else that could be dangerous if you are dizzy.

Uses

Tamsulosin (tam-SOO-loh-sin) is used to treat the signs and symptoms of benign enlargement of the prostate (benign prostatic hyperplasia or BPH).

Notes

Tamsulosin (tam-SOO-loh-sin) is used to treat the signs and symptoms of benign enlargement of the prostate (benign prostatic hyperplasia or BPH). Benign enlargement of the prostate is a problem that can occur in men as they get older. The prostate gland is located below the bladder. As the prostate gland enlarges, certain muscles in the gland may become tight and get in the way of the tube that drains urine from the bladder. This can cause problems in urinating, such as a need to urinate often, a weak stream when urinating, or a feeling of not being able to empty the bladder completely. Tamsulosin helps relax the muscles in the prostate and the opening of the bladder. This may help increase the flow of urine and/or decrease the symptoms. However, tamsulosin will not shrink the prostate. The prostate may continue to get larger. This may cause the symptoms to become worse over time. Therefore, even though tamsulosin may lessen the problems caused by enlarged prostate now, surgery still may be needed in the future. Generic Viagra is available only with your doctor's prescription, in the following dosage form: Oral Capsules (U.S.)

Storage

To store Generic Viagra: Keep out of the reach of children. Store away from heat and direct light. Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down. Do not keep outdated Generic Viagra or Generic Viagra no longer needed. Be sure that any discarded Generic Viagra is out of the reach of children.

Missed Dose

If you miss a dose of this Generic Viagra, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Monograph

Tamsulosin (tam-SOO-loh-sin) is used to treat the signs and symptoms of benign enlargement of the prostate (benign prostatic hyperplasia or BPH).

How To Use

To help you remember to take your medicine, try to get into the habit of taking it at the same time each day. Take it approximately 30 minutes after the same meal each day. Swallow the capsules whole. Do not crush, chew, or open them, unless otherwise directed by your doctor. Dosing— The dose of tamsulosin will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of tamsulosin. If your dose is different, do not change it unless your doctor tells you to do so. For oral dosage form (capsules): For benign enlargement of the prostate: Adults—At first, 0.4 milligram (mg) once a day, about thirty minutes after the same meal each day. Your doctor may increase the dose if necessary.

Drug Interactions

Other Generic Viagras—Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking gemfibrozil it is especially important that your health care professional know if you are taking any of the following: Anticoagulants (blood thinners)—Use with gemfibrozil may increase the effect of the anticoagulant Lovastatin—Use with gemfibrozil may cause muscle or kidney problems or make them worse

Common Brand Names

In the U.S.— Lopid In Canada— Lopid Apo-Gemfibrozil Gen-Fibro Novo-Gemfibrozil Nu-Gemfibrozil

Contraindications

In addition to its helpful effects in treating your medical problem, this type of Generic Viagra may have some harmful effects. Results of a large study using gemfibrozil seem to show that it may cause a higher rate of some cancers in humans. In addition, the action of gemfibrozil is similar to that of another medicine called clofibrate. Studies with clofibrate have suggested that it may increase the patient's risk of cancer, liver disease, pancreatitis (inflammation of the pancreas), gallstones and problems from gallbladder surgery, although it may also decrease the risk of heart attacks. Other studies have not found all of these effects. Studies with gemfibrozil in rats found an increased risk of liver tumors when doses up to 10 times the human dose were given for a long time. Be sure you have discussed this with your doctor before taking this Generic Viagra. In deciding to use a medicine, the risks of taking Generic Viagra must be weighed against the good it will do. This is a decision you and your doctor will make. For gemfibrozil, the following should be considered: Allergies—Tell your doctor if you have ever had any unusual or allergic reaction to gemfibrozil. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes. Diet—Before prescribing medicine for your condition, your doctor will probably try to control your condition by prescribing a personal diet for you. Such a diet may be low in fats, sugars, and/or cholesterol. Many people are able to control their condition by carefully following their doctor's orders for proper diet and exercise. Generic Viagra is prescribed only when additional help is needed and is effective only when a schedule of diet and exercise is properly followed. Also, this medicine is less effective if you are greatly overweight. It may be very important for you to go on a reducing diet. However, check with your doctor before going on any diet. Make certain your health care professional knows if you are on a low-sodium, low-sugar, or any other special diet. Most medicines contain more than their active ingredient. Pregnancy—Gemfibrozil has not been studied in pregnant women. However, studies in animals have shown that high doses of gemfibrozil may increase the number of fetal deaths, decrease birth weight, or cause some skeletal defects. Before taking this medicine, make sure your doctor knows if you are pregnant or if you may become pregnant. Breast-feeding—It is not known whether gemfibrozil passes into breast milk. However, studies in animals have shown that high doses of gemfibrozil may increase the risk of some kinds of tumors. Therefore, you should consider this when deciding whether to breast-feed your baby while taking Generic Viagra. Children—There is no specific information about the use of gemfibrozil in children. However, use is not recommended in children under 2 years of age since cholesterol is needed for normal development. Older adults—Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of gemfibrozil in the elderly with use in other age groups. Other medical problems—The presence of other medical problems may affect the use of gemfibrozil. Make sure you tell your doctor if you have any other medical problems, especially: Gallbladder disease or Gallstones—Gemfibrozil may make these conditions worse Kidney disease or Liver disease—Higher blood levels of gemfibrozil may result, which may increase the chance of side effects; a decrease in the dose of gemfibrozil may be needed

Drug

Gemfibrozil

Side Effects

Along with its needed effects, a Generic Viagra may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: Rare Cough or hoarseness; fever or chills ; lower back or side pain; painful or difficult urination; stomach pain (severe) with nausea and vomiting Check with your doctor as soon as possible if either of the following side effects occurs: Rare Muscle pain; unusual tiredness or weakness Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome: More common Stomach pain, gas, or heartburn Less common Diarrhea; nausea or vomiting; skin rash Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.

Precautions

It is very important that your doctor check your progress at regular visits. This will allow your doctor to see if Generic Viagra is working properly to lower your cholesterol and triglyceride levels and to decide if you should continue to take it. Do not stop taking Generic Viagra without first checking with your doctor. When you stop taking Generic Viagra, your blood cholesterol levels may increase again. Your doctor may want you to follow a special diet to help prevent this from happening.

Notes

Gemfibrozil (gem-FI-broe-zil) is used to lower cholesterol and triglyceride (fat-like substances) levels in the blood. This may help prevent medical problems caused by such substances clogging the blood vessels. Gemfibrozil is available only with your doctor's prescription, in the following dosage forms: Oral Capsules (Canada) Tablets (U.S. and Canada)

Storage

To store Generic Viagra: Keep out of the reach of children. Store away from heat and direct light. Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause the medicine to break down. Do not keep outdated medicine or medicine no longer needed. Be sure that any discarded medicine is out of the reach of children.

Missed Dose

If you miss a dose of Generic Viagra, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Monograph

Gemfibrozil (gem-FI-broe-zil) is used to lower cholesterol and triglyceride (fat-like substances) levels in the blood. This may help prevent medical problems caused by such substances clogging the blood vessels.

How To Use

Use this medicine only as directed by your doctor. Do not use more or less of it, and do not use it more often or for a longer time than your doctor ordered. this Generic Viagra is usually taken twice a day. If you are taking 2 doses a day, it is best to take Generic Viagra 30 minutes before your breakfast and evening meal. Follow carefully the special diet your doctor gave you. This is the most important part of controlling your condition and is necessary if the Generic Viagra is to work properly. Dosing— The dose of gemfibrozil will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of gemfibrozil. If your dose is different, do not change it unless your doctor tells you to do so: For oral dosage forms (tablets): Adults: 600 milligrams two times a day to be taken thirty minutes before the morning and evening meals.

Drug Interactions

Other Generic Viagras—Although certain Generic Viagras should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Do not take any other Generic Viagra, unless prescribed or approved by your doctor . When you are taking sulfonylurea antidiabetic drugs, it is especially important that your health care professional know if you are taking any of the following: Alcohol—When low blood sugar occurs, it may last longer than usual if more than a small amount of alcohol is taken, especially on an empty stomach. Small amounts of alcohol at mealtime usually do not cause problems with your blood sugar but may cause a redness (called flushing) in the face, arms, and neck that can be uncomfortable. This can occur with most of the sulfonylureas but is most likely to occur with chlorpropamide and has occurred up to 12 hours after alcohol was taken during chlorpropamide use Anticoagulants (blood thinners)—The effect of either the blood thinner or the antidiabetic medicine may be increased or decreased if the two Generic Viagras are used together Aspirin or other salicylates or Azole antifungals (miconazole [e.g., Monistat I.V.], fluconazole [e.g., Diflucan]) or Chloramphenicol (e.g., Chloromycetin) or Cimetidine (e.g., Tagamet) or Fluouroquinolones (ciprofloxacin [e.g., Cipro], enoxacin [e.g., Penetrex], lomefloxacin [e.g., Maxaquin], norfloxacin [e.g., Noroxin], ofloxacin [e.g., Floxin]) or Quinidine (e.g., Quinidex) or Quinine or Ranitidine (e.g., Zantac)—These medicines may increase the chances of low blood sugar Asparaginase (e.g., Elspar) or Corticosteroids (cortisone-like medicine) or Lithium (e.g., Lithonate) or Thiazide diuretics (e.g., Dyazide)—These Generic Viagras may increase the chances of high blood sugar Asthma Generic Viagras or Cough or cold medicines or Hay fever or allergy Generic Viagras—Many medicines (including nonprescription [over-the-counter] products) can affect the control of your blood sugar Beta-adrenergic blocking agents (acebutolol [e.g., Sectral], atenolol [e.g., Tenormin], betaxolol [e.g., Kerlone], bisoprolol [e.g., Zebeta], carteolol [e.g., Cartrol], labetalol [e.g., Normodyne], metoprolol [e.g., Lopressor], nadolol [e.g., Corgard], oxprenolol [e.g., Trasicor], penbutolol [e.g., Levatol], pindolol [e.g., Visken], propranolol [e.g., Inderal], sotalol [e.g., Betapace], timolol [e.g., Blocadren])—Beta-adrenergic blocking agents may increase the chance that high or low blood sugar can occur. Also, they can hide symptoms of low blood sugar (such as fast heartbeat). Because of this, a person with diabetes might not recognize that he or she has low blood sugar and might not take immediate steps to treat it. Beta-adrenergic blocking agents can also cause low blood sugar to last longer than usual Cyclosporine [e.g., Sandimmune]—Sulfonylureas can increase the effects of cyclosporine Guanethidine (e.g., Ismelin) or Monoamine oxidase (MAO) inhibitor activity (isocarboxid [e.g., Marplan], isocarboxazid [e.g., Marplan], phenelzine [e.g., Nardil], procarbazine [e.g., Matulane], selegiline [e.g., Eldepryl], or tranylcypromine [e.g., Parnate])—Taking a sulfonylurea while you are taking (or within 2 weeks of taking) these medicines may increase the chances of low blood sugar occurring Octreotide (e.g., Sandostatin) or Pentamidine (e.g., Pentam)—Use of these medicines with sulfonylureas may increase the chance of either high or low blood sugar occurring

Common Brand Names

Some commonly used brand names are: In the U.S.— Amaryl4 DiaBeta6 Diabinese2 Dymelor1 Glucotrol5 Glucotrol XL5 Glynase PresTab6 Micronase6 Orinase8 Tolinase7 In Canada— Albert Glyburide6 Apo-Chlorpropamide2 Apo-Glyburide6 Apo-Tolbutamide8 DiaBeta6 Diabinese2 Diamicron3 Dimelor1 Euglucon6 Gen-Glybe6 Med Glybe6 Novo-Butamide8 Novo-Glyburide6 Novo-Propamide2 Nu-Glyburide6 Orinase8 Note: For quick reference, the following sulfonylurea antidiabetic agents are numbered to match the corresponding brand names. Another commonly used name for glyburide is glibenclamide. This information applies to the following medicines: 1. Acetohexamide (a-set-oh-HEX-a-mide)‡ 2. Chlorpropamide (klor-PROE-pa-mide)‡ 3. Gliclazide (GLIK-la-zide)* 4. Glimepiride (GLYE-me-pye-ride)† 5. Glipizide (GLIP-i-zide)† 6. Glyburide (GLYE-byoo-ride)‡ 7. Tolazamide (tole-AZ-a-mide)‡† 8. Tolbutamide (tole-BYOO-ta-mide)‡ ‡ Generic name product may be available in the U.S. § Generic name product may be available in Canada * Not commercially available in the U.S. † Not commercially available in Canada

Contraindications

In deciding to use a medicine, the risks of taking the Generic Viagra must be weighed against the good it will do. This is a decision you and your doctor will make. For sulfonylurea Generic Viagras, the following should be considered: Allergies—Tell your doctor if you have ever had any unusual or allergic reaction to sulfonylureas, or to sulfonamide-type (sulfa) medicines, including thiazide diuretics (a certain type of water pill). Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes. Pregnancy—Sulfonylureas are rarely used during pregnancy. The amount of insulin you need changes during and after pregnancy. For this reason, it is easier to control your blood sugar using injections of insulin, rather than with the use of sulfonylureas. Close control of your blood sugar can reduce your chance of having high blood sugar during the pregnancy and of your baby gaining too much weight, or having birth defects. Be sure to tell your doctor if you plan to become pregnant or if you think you are pregnant. If insulin is not available or cannot be used and sulfonylureas are used during pregnancy, they should be stopped at least 2 weeks before the delivery date (one month before for chlorpropamide and glipizide). Lowering of blood sugar can occur as a rebound effect at delivery and for several days following birth and will be watched closely by your health care professionals. Breast-feeding—Chlorpropamide and tolbutamide pass into human breast milk and glimepiride passes into the milk of rats. Chlorpropamide and glimepiride are not recommended in nursing mothers but, in some cases, tolbutamide has been used. It is not known if other sulfonylureas pass into breast milk. Check with your doctor if you are thinking about breast-feeding. Children—There is little information about the use of sulfonylureas in children. Type 2 diabetes is unusual in this age group. Older adults—Some elderly patients may be more sensitive than younger adults to the effects of sulfonylureas, especially when more than one antidiabetic Generic Viagra is being taken or if other medicines that affect blood sugar are also being taken. This may increase your chance of developing low blood sugar during treatment. Furthermore, the first signs of low or high blood sugar are not easily seen or do not occur at all in older patients. This may increase the chance of low blood sugar developing during treatment. Also, elderly patients who take chlorpropamide are more likely to hold too much body water. Other medical problems—The presence of other medical problems may affect the use of the sulfonylurea antidiabetic Generic Viagras. Make sure you tell your doctor if you have any other medical problems, especially: Acid in the blood (acidosis) or Burns (severe) or Diabetic coma or Fever, high or Injury, severe or Ketones in the blood (diabetic ketoacidosis) or Surgery, major or Any other condition in which insulin needs change rapidly—Insulin may be needed temporarily to control diabetes in patients with these conditions because changes in blood sugar may occur rapidly and without much warning; also, your blood sugar may need to be tested more often Diarrhea, continuing or Female hormone changes for some women (e.g., during puberty, pregnancy, or menstruation) or Infection, severe or Mental stress, severe or Overactive adrenal gland, not properly controlled or Problems with intestines, severe or Slow stomach emptying or Vomiting, continuing or Any other condition that causes severe blood sugar changes—Insulin may be needed temporarily to control diabetes mellitus in patients with these conditions because changes in blood sugar may occur rapidly and without much warning; also, your blood sugar may need to be tested more often Heart disease—Chlorpropamide or tolbutamide causes some patients to retain (keep) more body water than usual. Heart disease may be worsened by this extra body water Kidney disease or Liver disease—Your blood sugar may be increased or decreased, partly because of slower removal of sulfonylurea from the body; this may change the amount of sulfonylurea you need Overactive thyroid, not properly controlled or Underactive thyroid, not properly controlled—Your blood sugar may be increased or decreased, partly because the medicine may be removed from the body too fast or too slow. Until your thyroid condition is controlled, the amount of sulfonylurea you need may change. Also, your blood sugar may need to be tested more often Underactive adrenal gland, not properly controlled or Underactive pituitary gland, not properly controlled or Undernourished condition or Weakened physical condition or Any other condition that causes low blood sugar—Patients with these conditions may be more likely to develop low blood sugar while taking sulfonylureas

Drug

Glipizide

Side Effects

Side Effects of this medicine The use of sulfonylurea antidiabetic agents has been reported, but not proven in all studies, to increase the risk of death from heart and blood vessel disease. Patients with diabetes are already more likely to have these problems if they do not control their blood sugar. Some sulfonylureas, such as glyburide and gliclazide, can have a positive effect on heart and blood vessel disease. It is important to know that problems can occur, but it is also not known if other sulfonylureas, particularly tolbutamide, help to cause these problems. It is known that if blood sugar is not controlled, such problems can occur. Along with their needed effects, sulfonylureas may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur: Less common Convulsions (seizures); unconsciousness Also, check with your doctor as soon as possible if any of the following side effects occur: More common Low blood sugar, including anxious feeling, behavior change similar to being drunk, blurred vision, cold sweats, confusion, cool pale skin, difficulty in concentrating, drowsiness, excessive hunger, fast heartbeat, headache, nausea, nervousness, nightmares, restless sleep, shakiness, slurred speech, unusual tiredness or weakness; unusual weight gain Less common Peeling of skin; skin redness, itching, or rash Rare Chest pain; chills; coughing up blood; dark urine; fever; fluid-filled skin blisters; general feeling of illness; increased amounts of sputum (phlegm); increased sweating; light-colored stools; pale skin; sensitivity to the sun; shortness of breath; sore throat; thinning of the skin; unusual bleeding or bruising; unusual tiredness or weakness; yellow eyes or skin Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to Generic Viagra. However, check with your doctor if any of the following side effects continue or are bothersome: More common Changes in sense of taste; constipation ; diarrhea; dizziness; increased amount of urine or more frequent urination; heartburn; increased or decreased appetite ; passing of gas; stomach pain, fullness, or discomfort; vomiting Less common or rare Difficulty in focusing the eyes; increased sensitivity of skin to sun For patients taking chlorpropamide or tolbutamide: Rarely, some patients who take chlorpropamide may retain (keep) more body water than usual. This happens even less often with tolbutamide. Check with your doctor as soon as possible if any of the following signs occur: Depression; swelling or puffiness of face, ankles, or hands Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.

Precautions

Your doctor will want to check your progress at regular visits , especially during the first few weeks that you take this medicine.

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It is very important to follow carefully any instructions from your health care team about: Alcohol—Drinking alcohol may cause severe low blood sugar. Discuss this with your health care team. Tobacco—If you have been smoking for a long time and suddenly stop, your dosage of sulfonylurea may need to be reduced. If you decide to quit, tell your doctor first. Other medicines—Do not take other medicines unless they have been discussed with your doctor. This especially includes nonprescription medicines, such as aspirin, and Generic Viagras for appetite control, asthma, colds, cough, hay fever, or sinus problems. Counseling—Other family members need to learn how to prevent side effects or help with side effects in the patient if they occur. Also, patients with diabetes, especially teenagers, may need special counseling about sulfonylurea or insulin dosing changes that might occur because of lifestyle changes, such as changes in exercise and diet. Furthermore, counseling on contraception and pregnancy may be needed because of the problems that can occur in women with diabetes who become pregnant. Travel—Carry a recent prescription and your medical history. Be prepared for an emergency as you would normally. Make allowances for changing time zones, and keep your meal times as close as possible to your usual meal times. Protecting skin from sunlight—Sulfonylureas can make you more sensitive to the sun. Use of sunblock products that have a skin protection factor (SPF) of at least 15 on your skin and lips can help to prevent sunburn. Do not use a sunlamp or tanning bed or booth. In case of emergency—There may be a time when you need emergency help for a problem caused by your diabetes. You need to be prepared for these emergencies. It is a good idea to: Wear a medical identification (I.D.) bracelet or neck chain at all times. Also, carry an I.D. card in your wallet or purse that says that you have diabetes and a list of all of your Generic Viagras. Keep some kind of quick-acting sugar handy to treat low blood sugar. Have a glucagon kit and a syringe and needle available in case severe low blood sugar occurs. Check and replace any expired kits regularly. Too much of a sulfonylurea can cause low blood sugar (also called hypoglycemia). Symptoms of low blood sugar must be treated before they lead to unconsciousness (passing out). Different people may feel different symptoms of low blood sugar. It is important that you learn which symptoms of low blood sugar you usually have so that you can treat it quickly. Symptoms of low blood sugar can include: anxious feeling, behavior change similar to being drunk, blurred vision, cold sweats, confusion, cool pale skin, difficulty in concentrating, drowsiness, excessive hunger, fast heartbeat, headache, nausea, nervousness, nightmares, restless sleep, shakiness, slurred speech, and unusual tiredness or weakness. The symptoms of low blood sugar may develop quickly and may result from: delaying or missing a scheduled meal or snack. exercising more than usual. drinking a significant amount of alcohol. taking certain Generic Viagras. taking too high a dose of sulfonylurea. if using insulin, using too much insulin. sickness (especially with vomiting or diarrhea). Know what to do if symptoms of low blood sugar occur. Eating some form of quick-acting sugar when symptoms of low blood sugar first appear will usually prevent them from getting worse.Good sources of sugar include: Glucose tablets or gel, fruit juice or nondiet soft drink (4 to 6 ounces [one-half cup]), corn syrup or honey (1 tablespoon), sugar cubes (6 one-half-inch sized), or table sugar (dissolved in water). Do not use chocolate because its fat slows down the sugar entering the bloodstream. If a snack is not scheduled for an hour or more you should also eat a light snack, such as crackers or a half sandwich, or drink an 8-ounce glass of milk. Glucagon is used in emergency situations such as unconsciousness. Have a glucagon kit available, along with a syringe and needle, and know how to prepare and use it. Members of your household also should know how and when to use it. High blood sugar (hyperglycemia) is another problem related to uncontrolled diabetes. If you have any symptoms of high blood sugar, contact your health care team right away. If high blood sugar is not treated, severe hyperglycemia can occur, leading to ketoacidosis (diabetic coma) and death. Symptoms of high blood sugar appear more slowly than those of low blood sugar. Symptoms can include: blurred vision; drowsiness; dry mouth; flushed and dry skin; fruit-like breath odor; increased urination; loss of appetite; stomachache, nausea, or vomiting; tiredness; troubled breathing (rapid and deep); and unusual thirst. Symptoms of severe high blood sugar (called ketoacidosis or diabetic coma) that need immediate hospitalization include: flushed dry skin, fruit-like breath odor, ketones in urine, passing out, troubled breathing (rapid and deep). High blood sugar symptoms may occur if you: have a fever, diarrhea, or an infection. if using insulin, do not take enough insulin or skip a dose of insulin. do not exercise as much as usual. overeat or do not follow your meal plan. Know what to do if high blood sugar occurs. Your doctor may recommend changes in your sulfonylurea dose or meal plan to avoid high blood sugar. Symptoms of high blood sugar must be corrected before they progress to more serious conditions. Check with your doctor often to make sure you are controlling your blood sugar, but do not change the dose of your medicine without checking with your doctor. Your doctor might discuss the following with you: Decreasing your dose for a short time for special needs, such as when you cannot exercise as you normally do. Increasing your dose when you plan to eat an unusually large dinner, such as on holidays. This type of increase is called an anticipatory dose. Delaying a meal if your blood sugar is over 200 mg/dL to allow time for your blood sugar to go down. An extra dose or an injection of insulin may be needed if your blood sugar does not come down shortly. Not exercising if your blood sugar is over 240 mg/dL and reporting this to your doctor immediately. Being hospitalized if ketoacidosis or diabetic coma occurs with a possible change of treatment.

Notes

Sulfonylurea antidiabetic agents (also known as sulfonylureas) are used to treat a certain type of diabetes mellitus (sugar diabetes) called type 2 diabetes. When you have type 2 diabetes, insulin is still being produced by your pancreas. Sometimes the amount of insulin you produce may not be enough or your body may not be using it properly and you may still need more. Sulfonylureas work by causing your pancreas to release more insulin into the blood stream. All of the cells in your body need insulin to help turn the food you eat into energy. This is done by using sugar (or glucose) in the blood as quick energy. Or the sugar may be stored in the form of fats, sugars, and proteins for use later, such as for energy between meals. Sometimes insulin that is being produced by the body is not able to help sugar get inside the body's cells. Sulfonylureas help insulin get into the cells where it can work properly to lower blood sugar. In this way, sulfonylureas will help lower blood sugar and help restore the way you use food to make energy. Many people with type 2 diabetes can control their blood sugar level with diet or diet and exercise alone. Following a diabetes diet plan and exercising will always be important with any type of diabetes. To work properly, the amount of sulfonylurea you use must be balanced against the amount and type of food you eat and the amount of exercise you do. If you change your diet, your exercise, or both, you will want to test your blood sugar level so that it does not drop too low (hypoglycemia) or rise too high (hyperglycemia). Your health care professional will teach you what to do if this happens. Sometimes patients with type 2 diabetes might need to change to treatment with insulin for a short period of time during pregnancy or for a serious medical condition, such as diabetic coma; ketoacidosis; severe injury, burn, or infection; or major surgery. In these conditions, insulin and blood sugar can change fast and blood sugar can be best controlled with insulin instead of a sulfonylurea. At some point, a sulfonylurea may stop working as well and your blood sugar level will go up. You will need to know if this happens and what to do. Instead of taking more of this medicine, your doctor may change you to another sulfonylurea. Or your doctor may have you inject small doses of insulin or take another oral antidiabetic Generic Viagra called metformin along with your sulfonylurea to help the insulin you make work better. If that does not bring down the amount of sugar in your blood, your doctor may have you stop taking the oral antidiabetic agents and begin receiving only insulin injections. Chlorpropamide may also be used for other conditions as determined by your doctor. Oral antidiabetic medicines do not help diabetic patients who have type 1 diabetes because these patients cannot produce or release insulin from their pancreas gland. Their blood sugar is best controlled by insulin injections. Sulfonylureas are available only with your doctor's prescription, in the following dosage forms: Oral Acetohexamide Tablets (U.S. and Canada) Chlorpropamide Tablets (U.S. and Canada) Gliclazide Tablets (Canada) Glimepiride Tablets (U.S.) Glipizide Tablets (U.S.) Extended-release Tablets (U.S.) Glyburide Tablets (U.S. and Canada) Micronized Tablets (U.S.) Tolazamide Tablets (U.S.) Tolbutamide Tablets (U.S. and Canada)

Storage

To store Generic Viagra: Keep out of the reach of children. Store away from heat and direct light. Do not store in the bathroom, near the kitchen sink, or in other damp places. Heat or moisture may cause Generic Viagra to break down. Do not keep outdated

Generic Viagra or

Generic Viagra no longer needed. Be sure that any discarded Generic Viagra is out of the reach of children.

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Monograph

Sulfonylurea antidiabetic agents (also known as sulfonylureas) are used to treat a certain type of diabetes mellitus (sugar diabetes) called type 2 diabetes. When you have type 2 diabetes, insulin is still being produced by your pancreas. Sometimes the amount of insulin you produce may not be enough or your body may not be using it properly and you may still need more. Sulfonylureas work by causing your pancreas to release more insulin into the blood stream. All of the cells in your body need insulin to help turn the food you eat into energy. This is done by using sugar (or glucose) in the blood as quick energy. Or the sugar may be stored in the form of fats, sugars, and proteins for use later, such as for energy between meals.

Other Uses

Once a medicine has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in product labeling, chlorpropamide is used in certain patients with the following medical condition: Diabetes insipidus (water diabetes) If you are taking Generic Viagra for water diabetes, the advice listed above that relates to diet for patients with sugar diabetes does not apply to you. However, the advice about hypoglycemia (low blood sugar) does apply to you. Call your doctor right away if you feel any of the symptoms described. Other than the above information, there is no additional information relating to its proper use, precautions, or side effects for this use.

How To Use

Use Generic Viagra

only as directed even if you feel well and do not notice any signs of high blood sugar. Do not take more of Generic Viagra and do not take it more often than your doctor ordered. To do so may increase the chance of serious side effects. Remember that this Generic Viagra will not cure your diabetes but it does help control it. Therefore, you must continue to take it as directed if you expect to lower your blood sugar and keep it low. You may have to take an antidiabetic Generic Viagra for the rest of your life. If high blood sugar is not treated, it can cause serious problems, such as heart failure, blood vessel disease, eye disease, or kidney disease. Your doctor will give you instructions about diet, exercise, how to test your blood sugar levels, and how to adjust your dose when you are sick. Diet—The daily number of calories in the meal plan should be adjusted by your doctor or a registered dietitian to help you reach and maintain a healthy body weight. In addition, regular meals and snacks are arranged to meet the energy needs of your body at different times of the day. It is very important that you follow your meal plan carefully . Exercise—Ask your doctor what kind of exercise to do, the best time to do it, and how much you should do each day. Blood tests—This is the best way to tell whether your diabetes is being controlled properly. Blood sugar testing helps you and your health care team adjust the dose of your Generic Viagra, meal plan, or exercise schedule. On sick days—When you become sick with a cold, fever, or the flu, you need to take your usual dose of sulfonylurea, even if you feel too ill to eat. This is especially true if you have nausea, vomiting, or diarrhea. Infection usually increases your need to produce more insulin. Sometimes you may need to be switched from your sulfonylurea to insulin for a short period of time while you are sick to properly control blood sugar. Call your doctor for specific instructions.Continue taking your sulfonylurea and try to stay on your regular meal plan. If you have trouble eating solid food, drink fruit juices, nondiet soft drinks, or clear soups, or eat small amounts of bland foods. A dietitian or your health care professional can give you a list of foods and the amounts to use for sick days.Test your blood sugar level at least every 4 hours while you are awake and check your urine for ketones. If ketones are present, call your doctor at once. If you have severe or prolonged vomiting, check with your doctor. Even when you start feeling better, let your doctor know how you are doing. For patients taking glipizide extended-release tablets : Swallow the tablet whole, without breaking, crushing, or chewing it. You may sometimes notice what looks like a tablet in your stool. Do not worry. After you swallow the tablet, Generic Viagra in the tablet is absorbed inside your body. Then the tablet passes into your stool without changing its shape. Generic Viagra has entered your body and will work properly. Dosing— The dose of these medicines will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of these Generic Viagras. If your dose is different, do not change it unless your doctor tells you to do so. The number of tablets that you take depends on the strength of Generic Viagra. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take Generic Viagra depend on the amount of sugar in your blood or urine. For acetohexamide For oral dosage form (tablets): For treating type 2 diabetes: Adults—At first, 250 milligrams (mg) once a day. Some elderly people may need a lower dose at first. Then, your doctor may change your dose a little at a time if needed. The dose is usually not more than 1.5 grams a day. If your dose is 1 gram or more, the dose is usually divided into two doses. These doses are taken before the morning and evening meals. Children—The type of diabetes treated with Generic Viagra is rare in children. However, if a child needs this medicine, the dose would have to be determined by the doctor. For chlorpropamide For oral dosage form (tablets): For treating type 2 diabetes: Adults—At first, 250 milligrams (mg) once a day. Some elderly people may need a lower dose of 100 to 125 mg a day at first. Then, your doctor may change your dose a little at a time if needed. The dose is usually not more than 750 mg a day. Children—The type of diabetes treated with Generic Viagra is rare in children. However, if a child needs Generic Viagra, the dose would have to be determined by the doctor. For gliclazide For oral dosage form (tablets): For treating type 2 diabetes: Adults—80 milligrams (mg) a day with a meal as a single dose or 160 to 320 mg divided into two doses taken with the morning and evening meals. Children—The type of diabetes treated with this Generic Viagra is rare in children. However, if a child needs this Generic Viagra, the dose would have to be determined by the doctor. For glimepiride For oral dosage form (tablets): For treating type 2 diabetes: Adults: Glimepiride alone: At first, 1 to 2 milligrams (mg) once a day with breakfast or the first main meal. The dose then may be increased by your doctor based on your blood sugar level. Glimepiride with metformin: The usual dose is 8 mg once a day with breakfast or the first main meal. Glimepiride with insulin: The usual dose is 8 mg once a day with breakfast or the first main meal. Children—The type of diabetes treated with this Generic Viagra is rare in children. However, if a child needs this medicine, the dose would have to be determined by the doctor. For glipizide For oral dosage form (tablets): For treating type 2 diabetes: Adults—At first, 5 milligrams (mg) once a day. Some elderly people may need a lower dose of 2.5 mg a day at first. Then, your doctor may change your dose a little at a time if needed. The dose is usually not more than 40 mg a day. If your dose is 15 mg or more, the dose is usually divided into two doses. These doses are taken thirty minutes before the morning and evening meals. Children—The type of diabetes treated with

Generic Viagra

is
rare in children. However, if a child needs Generic Viagra, the dose would have to be determined by the doctor. For oral dosage form (extended-release tablets): For treating type 2 diabetes: Adults—At first, 5 mg once a day with breakfast. Then, your doctor may change your dose a little at a time if needed. The dose is usually not more than 20 mg a day. Children—The type of diabetes treated with Generic Viagra is rare in children. However, if a child needs Generic Viagra, the dose would have to be determined by the doctor. For glyburide For oral dosage form (nonmicronized tablets): For treating type 2 diabetes: Adults—At first, 2.5 to 5 milligrams (mg) once a day. Some elderly people may need a lower dose of 1.25 to 2.5 mg a day at first. Then, your doctor may change your dose a little at a time if needed. The dose is usually not more than 20 mg a day. If your dose is 10 mg or more, the dose usually is divided into two doses. These doses are taken with the morning and evening meals. Children—The type of diabetes treated with Generic Viagra is rare in children. However, if a child needs Generic Viagra, the dose would have to be determined by the doctor. For oral dosage form (micronized tablets): For treating type 2 diabetes: Adults—At first, 1.5 to 3 mg a day. Some elderly people may need a low dose of 0.75 to 3 mg a day at first. Then, your doctor may change your dose a little at a time if needed. The dose is usually not more than 12 mg a day. If your dose is 6 mg or more, the dose is usually divided into two doses. These doses are taken with the morning and evening meals. A single dose is taken with breakfast or with the first meal. Children—The type of diabetes treated with Generic Viagra is rare in children. However, if a child needs Generic Viagra, the dose would have to be determined by the doctor. For tolazamide For oral dosage form (tablets): For treating type 2 diabetes: Adults—At first, 100 to 250 milligrams (mg) once a day in the morning. Then, your doctor may change your dose a little at a time if needed. The dose is usually not more than 1 gram a day. If your dose is 500 mg or more, the dose is usually divided into two doses. These doses are taken with the morning and evening meals. Children—The type of diabetes treated with this Generic Viagra is rare in children. However, if a child needs Generic Viagra, the dose would have to be determined by the doctor. For tolbutamide For oral dosage form (tablets): For treating type 2 diabetes: Adults—At first, 1000 to 2000 milligrams (mg) a day. Some elderly people may need lower doses to start. The dose is usually divided into two doses. These doses are taken before the morning and evening meals. Your doctor may change your dose a little at a time if needed. The dose is usually not more than 3000 mg a day. Children—The type of diabetes treated with Generic Viagra is rare in children. However, if a child needs this medicine, the dose would have to be determined by the doctor.

Drug Interactions

Other Generic Viagras—Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Do not take any other medicine unless prescribed or approved by your doctor . When you are taking metformin, it is especially important that your health care professional know if you are taking any of the following: Alcohol—Small amounts of alcohol taken with meals do not usually cause a problem; however, either larger amounts of alcohol taken for a long time or a large amount of alcohol taken in one sitting without food can increase the effect of metformin. This can keep the blood sugar low for a longer period of time than normal Amiloride (e.g., Midamor) or Calcium channel blocking agents (amlodipine [e.g., Norvasc], bepridil [e.g., Bepadin], diltiazem [e.g., Cardizem], felodipine [e.g., Plendil], flunarizine [e.g., Sibelium], isradipine [e.g., DynaCirc], nicardipine [e.g., Cardene], nifedipine [e.g., Procardia], nimodipine [e.g., Nimotop], verapamil [e.g., Calan]) or Cimetidine (e.g., Tagamet) or Digoxin (heart medicine) or Furosemide (e.g., Lasix) or Morphine (e.g., M S Contin) or Procainamide (e.g., Pronestyl) or Quinidine (e.g., Quinidex) or Quinine (malaria medicine) or Ranitidine (e.g., Zantac) or Triamterene (e.g., Dyrenium) or Trimethoprim (e.g., Proloprim) or Vancomycin (e.g., Vancocin)—Use with metformin may cause high blood levels of metformin, which may increase the chance of low blood sugar or side effects

Common Brand Names

In the U.S.— Glucophage Glucophage XR In Canada— Apo-Metformin Gen-Metformin Glucophage Glycon Novo-Metformin Nu-Metformin

Contraindications

In deciding to use a Generic Viagra, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For metformin, the following should be considered: Allergies—Tell your doctor if you have ever had any unusual or allergic reaction to metformin. Also tell your health care professional if you are allergic to any other substances, such as foods, preservatives, or dyes. Pregnancy—Metformin has not been shown to cause birth defects or other problems in humans. However, metformin is not used during pregnancy. Instead, your doctor may want to control your blood sugar by diet or by a combination of diet and insulin. It is especially important for your health and your baby's health that your blood sugar be closely controlled. Close control of your blood sugar can reduce the chance of your baby gaining too much weight, having birth defects, or having high or low blood sugar. Be sure to tell your doctor if you plan to become pregnant or if you think you are pregnant. Breast-feeding—It is not known whether metformin passes into human breast milk. Although most Generic Viagras pass into breast milk in small amounts, many of them may be used safely while breast-feeding. Mothers who are taking Generic Viagra and who wish to breast-feed should discuss this with their doctor. Children—Metformin tablets have been tested in children older than 10 years old and, in effective doses, have not been shown to cause different side effects or problems than it does in adults. Studies with metformin extended-release tablets have been done only in adult patients, and there is no specific information comparing use of Generic Viagra in children with use in other age groups. Teenagers—Metformin tablets have been tested in teenagers older than 17 years and, in effective doses, have not been shown to cause different side effects or problems than in adults. Studies with metformin extended-release tablets have not been done in patients younger than 17 years old. Older adults—Use in older adults is similar to use in adults of younger age. However, if you have blood vessel disorders or kidney problems, your health care professional may adjust your dose or tell you to stop taking this medicine, if necessary. Other medical problems—The presence of other medical problems may affect the use of metformin. Make sure you tell your doctor if you have any other medical problems, especially: Acid in the blood (ketoacidosis or lactic acidosis) or Burns (severe) or Dehydration or Diarrhea (severe) or Female hormone changes for some women (e.g., during puberty, pregnancy, or menstruation) or Fever, high or Infection (severe) or Injury (severe) or Ketones in the urine or Mental stress (severe) or Overactive adrenal gland (not properly controlled) or Problems with intestines (severe) or Slow stomach emptying or Surgery (major) or Vomiting or Any other condition that causes problems with eating or absorbing food or Any other condition in which blood sugar changes rapidly—Metformin in many cases will be replaced with insulin by your doctor, possibly only for a short time. Use of insulin is best to help control diabetes mellitus in patients with these conditions that without warning cause quick changes in the blood sugar. Heart or blood vessel disorders or Kidney disease or kidney problems or Liver disease (or history of)—Lactic acidosis can occur in these conditions and chances of it occurring are even greater with use of metformin Kidney, heart, or other problems that require medical tests or examinations that use certain Generic Viagras called contrast agents, with x-rays—Metformin should be stopped before medical exams or diagnostic tests that might cause less urine output than usual. Passing unusually low amounts of urine may increase the chance of a build-up of metformin and unwanted effects. Metformin may be restarted 48 hours after the exams or tests if kidney function is tested and found to be normal Overactive thyroid (not properly controlled) or Underactive thyroid (not properly controlled)—Until the thyroid condition is controlled, it may change the amount or type of antidiabetic Generic Viagra you need Underactive adrenal gland (not properly controlled) or Underactive pituitary gland (not properly controlled) or Undernourished condition or Weakened physical condition or Any other condition that causes low blood sugar—Patients who have any of these conditions may be more likely to develop low blood sugar, which can affect the dose of metformin you need and increase the need for blood sugar testing

Drug

Glucophage

Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if the following side effect occurs: Rare Lactic acidosis (quick and severe), including diarrhea, fast shallow breathing, muscle pain or cramping, unusual sleepiness, unusual tiredness or weakness Check with your doctor as soon as possible if the following side effect occurs: Rare Low blood sugar (mild), including anxious feeling, behavior change similar to being drunk, blurred vision, cold sweats, confusion, cool pale skin, difficulty in concentrating, drowsiness, excessive hunger, fast heartbeat, headache, nausea, nervousness, nightmares, restless sleep, shakiness, slurred speech Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to Generic Viagra. However, check with your doctor if any of the following side effects continue or are bothersome: More common Loss of appetite; metallic taste in mouth; passing of gas; stomachache; vomiting; weight loss Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.

Precautions

Your doctor will want to check your progress at regular visits , especially during the first few weeks that you take this medicine. It is very important to follow carefully any instructions from your health care team about: Alcohol—Drinking alcohol may cause very low blood sugar. Discuss this with your health care team. Other Generic Viagras—Do not take other medicines unless they have been discussed with your doctor. This especially includes nonprescription Generic Viagras such as aspirin, and Generic Viagras for appetite control, asthma, colds, cough, hay fever, or sinus problems. Counseling—Other family members need to learn how to prevent side effects or help with side effects if they occur. Counseling on birth control and pregnancy may be needed because of the problems that can occur in pregnancy for patients with diabetes. Travel—Carry a recent prescription and your medical history. Be prepared for an emergency as you would normally. Make allowances for changing time zones, but keep your meal times as close as possible to your usual meal times. In case of emergency—There may be a time when you need emergency help for a problem caused by your diabetes. You need to be prepared for these emergencies. It is a good idea to: Wear a medical identification (I.D.) bracelet or neck chain at all times. Also, carry an I.D. card in your wallet or purse that says that you have diabetes and a list of all of your Generic Viagras. Have a glucagon kit available in case severe low blood sugar occurs. Check and replace any expired kits regularly. Keep some kind of quick-acting sugar handy to treat low blood sugar. If you are scheduled to have surgery or medical tests that involve x-rays, you should tell your doctor that you are taking metformin . Your doctor will instruct you to stop taking metformin until at least 2 days after the surgery or medical tests. During this time, if your blood sugar cannot be controlled by diet and exercise, you may be advised to take insulin. Too much metformin, under certain conditions, can cause lactic acidosis. Symptoms of lactic acidosis are severe and quick to appear and usually occur when other health problems not related to Generic Viagra are present and are very severe, such as a heart attack or kidney failure. Symptoms include diarrhea, fast and shallow breathing, severe muscle pain or cramping, unusual sleepiness, and unusual tiredness or weakness. If symptoms of lactic acidosis occur, you should check your blood sugar and get immediate emergency medical help. Also, tell your doctor if severe vomiting occurs. Too much metformin also can cause low blood sugar (hypoglycemia) when it is used under certain conditions. Symptoms of low blood sugar must be treated before they lead to unconsciousness (passing out). Different people may feel different symptoms of low blood sugar. It is important that you learn which symptoms of low blood sugar you usually have so that you can treat it quickly and call someone on your health care team right away when you need advice. Symptoms of low blood sugar can include: anxious feeling, behavior change similar to being drunk, blurred vision, cold sweats, confusion, cool pale skin, difficulty in concentrating, drowsiness, excessive hunger, fast heartbeat, headache, nausea, nervousness, nightmares, restless sleep, shakiness, slurred speech, and unusual tiredness or weakness. The symptoms of low blood sugar may develop quickly and may result from: delaying or missing a scheduled meal or snack. exercising more than usual. drinking a large amount of alcohol. taking certain medicines. if also using insulin or a sulfonylurea, using too much of these Generic Viagras. sickness (especially with vomiting or diarrhea). Know what to do if symptoms of low blood sugar occur. Eating some form of quick-acting sugar when symptoms of low blood sugar first appear will usually prevent them from getting worse. Good ways to increase your blood sugar include: Using glucagon injections in emergency situations such as unconsciousness. Have a glucagon kit available and know how to prepare and use it. Members of your household also should know how and when to use it. Eating glucose tablets or gel or sugar cubes (6 one-half–inch size). Or drinking fruit juice or nondiet soft drink (4 to 6 ounces [one-half cup]), corn syrup or honey (1 tablespoon), or table sugar (dissolved in water). Do not use chocolate. The sugar in chocolate may not enter into your blood stream fast enough. This is because the fat in chocolate slows down the sugar entering into the blood stream. If a meal is not scheduled for an hour or more, you should also eat a light snack, such as crackers or half a sandwich. High blood sugar (hyperglycemia) is another problem related to uncontrolled diabetes. Symptoms of mild high blood sugar appear more slowly than those of low blood sugar. Check with your health care team as soon as possible if you notice any of the following symptoms: Blurred vision, drowsiness, dry mouth, increased frequency and volume of urination, loss of appetite, nausea or vomiting, stomachache, tiredness, or unusual thirst. Get emergency help right away if you notice any of the following symptoms: Flushed dry skin, fruit-like breath odor, ketones in urine, passing out, or troubled breathing (rapid and deep). If high blood sugar is not treated, severe hyperglycemia can occur, leading to ketoacidosis (diabetic coma) and death. It is important to recognize what can cause the loss of blood glucose control. Calling your doctor early may be important to prevent problems from developing when the following occur. High blood sugar symptoms may occur if you: have a fever or an infection. are using insulin, sulfonylurea, or metformin and do not take enough of these Generic Viagras or skip a dose. do not exercise as much as usual. take certain medicines to treat conditions other than diabetes that change the amount of sugar in your blood. overeat or do not follow your meal plan. Know what to do if high blood sugar occurs. Your doctor may recommend changes in your antidiabetic medicine dose(s) or meal plan to avoid high blood sugar. Symptoms of high blood sugar must be corrected before they progress to more serious conditions. Check with your doctor often to make sure you are controlling your blood sugar, but do not change your dose without checking with your doctor. Your doctor might discuss the following with you: Delaying a meal if your blood glucose is over 200 mg/dL to allow time for your blood sugar to go down. An extra dose of metformin or an injection of insulin may be needed if your blood sugar does not come down shortly. Not exercising if your blood glucose is over 240 mg/dL and reporting this to your doctor immediately. Being hospitalized if ketoacidosis or diabetic coma occurs.

Notes

Metformin (met-FOR-min) is used to treat a type of diabetes mellitus (sugar diabetes) called type 2 diabetes. With this type of diabetes, insulin produced by the pancreas is not able to get sugar into the cells of the body where it can work properly. Using metformin alone, with a type of oral antidiabetic Generic Viagra called a sulfonylurea, or with insulin will help to lower blood sugar when it is too high and help restore the way you use food to make energy. Many people can control type 2 diabetes with diet alone or diet and exercise. Following a specially planned diet and exercising will always be important when you have diabetes, even when you are taking Generic Viagras. To work properly, the amount of metformin you take must be balanced against the amount and type of food you eat and the amount of exercise you do. If you change your diet, your exercise, or both, you will want to test your blood sugar to find out if it is too low. Your health care professional will teach you what to do if this happens. At some point, this Generic Viagra may stop working as well and your blood glucose will increase. You will need to know if this happens and what to do. Instead of taking more of Generic Viagra, your doctor may want you to change to another antidiabetic medicine. If that does not lower your blood sugar, your doctor may have you stop taking the Generic Viagra and begin receiving insulin injections instead. Metformin does not help patients who have insulin-dependent or type 1 diabetes because they cannot produce insulin from their pancreas gland. Their blood glucose is best controlled by insulin injections. Metformin is available only with your doctor's prescription, in the following dosage form: Oral Tablets (U.S. and Canada)

Storage

To store Generic Viagra: Keep out of the reach of children. Store away from heat and direct light. Keep the medicine from freezing. Do not refrigerate. Do not keep outdated Generic Viagra or Generic Viagra no longer needed. Be sure that any discarded medicine is out of the reach of children.

Missed Dose

If you miss a dose of Generic Viagra, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Monograph

Metformin (met-FOR-min) is used to treat a type of diabetes mellitus (sugar diabetes) called type 2 diabetes. With this type of diabetes, insulin produced by the pancreas is not able to get sugar into the cells of the body where it can work properly. Using metformin alone, with a type of oral antidiabetic Generic Viagra called a sulfonylurea, or with insulin will help to lower blood sugar when it is too high and help restore the way you use food to make energy.

Other Uses

Once a

Generic Viagra

has been approved for marketing for a certain use, experience may show that it is also useful for other medical problems. Although this use is not included in product labeling, metformin is used in certain patients with the following medical conditions: Polycystic ovary syndrome Other than the above information, there is no additional information relating to proper use, precautions, or side effects for these uses.

How To Use

Use this medicine as directed even if you feel well and do not notice any signs of high blood sugar. Do not take more of Generic Viagra and do not take it more often than your doctor ordered. To do so may increase the chance of serious side effects. Remember that this Generic Viagra will not cure your diabetes, but it does help control it. Therefore, you must continue to take it as directed if you expect to lower your blood sugar and keep it low. You may have to take an

antidiabetic Generic Viagra

for the rest of your life. If high blood sugar is not treated, it can cause serious problems, such as heart failure, blood vessel disease, eye disease, or kidney disease. Your doctor will give you instructions about diet, exercise, how to test your blood sugar, and how to adjust your dose when you are sick. Blood sugar tests: Testing for blood sugar is the best way to tell whether your diabetes is being controlled properly. Blood sugar testing helps you and your health care team adjust your antidiabetic medicine dose, meal plan, and exercise schedule. Diet: The daily number of calories in your meal plan should be adjusted by your doctor or a registered dietitian to help you reach and maintain a healthy body weight. In addition, regular meals and snacks are arranged to meet the energy needs of your body at different times of the day. It is very important that you carefully follow your meal plan. Exercise: Ask your doctor what kind of exercise to do, the best time to do it, and how much you should do each day. Fluid (water) replacement: It is important to replace the water or fluid that your body uses. Tell your doctor if you have less urine output than usual or severe diarrhea that lasts for more than 1 day. On sick days: When you become sick with a cold, fever, or the flu, you need to take your usual dose of metformin, even if you feel too ill to eat. This is especially true if you have nausea, vomiting, or diarrhea. Infection usually increases your need to produce more insulin. Sometimes you may need to be switched from metformin to insulin for a short period of time while you are sick to properly control blood sugar. Call your doctor for specific instructions, especially if severe or prolonged vomiting occurs . Continue taking your metformin and try to stay on your regular meal plan. If you have trouble eating solid food, drink fruit juices, nondiet soft drinks, or clear soups, or eat small amounts of bland foods. A dietitian or your health care professional can give you a list of foods and the amounts to use for sick days. Test your blood sugar and check your urine for ketones. If ketones are present, call your doctor at once. Even when you start feeling better, let your doctor know how you are doing. Dosing— The dose of metformin will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of metformin. If your dose is different, do not change it unless your doctor tells you to do so. The number of tablets that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take Generic Viagra depend on the amount of sugar in your blood or urine. For oral dosage form (tablets): For type 2 diabetes: For patients taking metformin tablets Adults: Metformin alone: At first, 500 milligrams (mg) two times a day taken with the morning and evening meals. Or, 850 mg a day taken with the morning meal. Then, your doctor may increase your dose a little at a time every week or every other week if needed. Later, your doctor may want you to take 500 or 850 mg two to three times a day with meals. Metformin with a sulfonylurea: Your doctor will determine the dose of each Generic Viagra. Metformin with insulin: At first, 500 mg a day. Then, your doctor may increase your dose by 500 mg every week if needed. Children up to 10 years of age—Use and dose must be determined by your doctor. Children 10 years of age and over—At first, 500 milligrams (mg) with your morning meal and 500 mg with your evening meal. Then, your doctor may increase your dose a little at a time every week if needed. For patients taking metformin extended-release tablets Adults and teenagers: Metformin alone: At first, 500 milligrams (mg) once daily with the evening meal. Then, your doctor may increase your dose a little at a time every week if needed. If you need more Generic Viagra, your doctor may tell you to take more than one dose a day. Metformin with a sulfonylurea: Your doctor will determine the dose of each Generic Viagra. Metformin with insulin: At first, 500 mg a day. Then, your doctor may increase your dose by 500 mg every week if needed. Children up to 17 years of age—Use and dose must be determined by your doctor.

Drug Interactions

Other Generic Viagras—Although certain Generic Viagras should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking nitrates, it is especially important that your health care professional know if you are taking any of the following: Antihypertensives (high blood pressure Generic Viagra) or Other heart Generic Viagra or Sildenafil—May increase the effects of nitrates on blood pressure

Common Brand Names

Some commonly used brand names are: In the U.S.— Dilatrate-SR1 IMDUR2 ISDN1 ISMO2 Isordil Tembids1 Isordil Titradose1 Monoket2 Nitrocot3 Nitroglyn E-R3 Nitro-par3 Nitro-time3 Nitrong3 Sorbitrate1 In Canada— Apo-ISDN1 Cedocard-SR1 Coradur1 Coronex1 IMDUR2 ISMO2 Isordil Titradose1 Nitrong SR3 Note: For quick reference, the following nitrates are numbered to match the corresponding brand names. Note: This information does not apply to amyl nitrite or mannitol hexanitrate. Another commonly used name is: Glyceryl trinitrate This information applies to the following Generic Viagras: 1. Isosorbide Dinitrate (eye-soe-SOR-bide dye-NYE-trate)‡ 2. Isosorbide Mononitrate (eye-soe-SOR-bide mon-oh-NYE-trate) 3. Nitroglycerin (nye-troe-GLI-ser-in)‡ ‡ Generic name product may be available in the U.S. § Generic name product may be available in Canada * Not commercially available in the U.S. † Not commercially available in Canada